How is globulin assessed in the laboratory?

Globulin is primarily assessed in the laboratory through total protein testing or serum protein electrophoresis. The total protein test measures the concentration of all proteins in the serum, including albumin and globulins. The serum protein electrophoresis method further separates serum proteins into different fractions based on their size and charge, allowing for a more detailed analysis of individual globulin fractions (e.g., alpha, beta, and gamma globulins).

This assessment is crucial for diagnosing and monitoring various conditions, including infections, inflammatory diseases, liver disease, and certain types of cancer. By providing a comprehensive analysis of protein levels and their distribution, laboratory professionals can identify abnormalities that may indicate underlying health issues.