What defines MDRO?

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The term MDRO stands for Multidrug-Resistant Organisms, which are defined by their resistance to multiple antibiotics that are typically effective against certain infections. The correct choice highlights that MDROs include specific organisms like C. difficile (C-diff) and Methicillin-resistant Staphylococcus aureus (MRSA).

C. difficile is a notable pathogen known for causing antibiotic-associated diarrhea, and MRSA is significant for causing a variety of infections, including skin and soft tissue infections, as well as more severe invasive infections. Both organisms illustrate the clinical relevance of MDROs as they pose challenges in treatment due to their resistance patterns, making them critical subjects of study and concern in healthcare settings.

The other options do not accurately represent what defines MDROs. For example, stating that they are susceptible to multiple antibiotics contradicts the essence of what makes an organism "multidrug-resistant." Describing them as extremely rare bacteria overlooks the fact that some MDROs, such as MRSA, are quite common in certain populations. Finally, the notion that they only cause gastrointestinal infections is misleading, as MDROs can affect various body systems and not just the gastrointestinal tract.

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