What does a positive coagulase test indicate?

A positive coagulase test is a specific diagnostic tool used to identify certain bacteria, particularly strains of Staphylococcus. The coagulase enzyme produced by some bacteria enables the conversion of fibrinogen in blood plasma into fibrin, resulting in clot formation. This test is primarily used to differentiate Staphylococcus aureus, which is coagulase-positive, from other species of Staphylococcus that do not produce this enzyme (coagulase-negative).

In the context of microbial identification, a positive coagulase test confirms the presence of coagulase-positive organisms, which is a key characterization for pathogens such as Staphylococcus aureus, known for its association with various infections, including skin infections, pneumonia, and sepsis. Thus, identifying the organism as coagulase positive has significant implications for clinical management and treatment options.