What is the definition of an amboceptor?

An amboceptor is defined as an immune body that links complement to an antigen. This means it acts as a bridge between the complement system and the antigen, facilitating the immune response. Amboceptors can attach to specific antigens through their Fab regions, while their Fc regions interact with complement proteins. This dual functionality is crucial as it enhances the opsonization and lysis of the target pathogen by coating it with complement proteins, thereby marking it for destruction by phagocytic cells.

The role of amboceptors is particularly significant in the context of antibody-mediated immunity and complement activation, which are vital components of the immune response in defending against infections and diseases.