What is the normal range for urine osmolality?

The normal range for urine osmolality is indeed quite broad, typically falling between 50 and 1400 mOsm/kg water. This range reflects the kidneys' ability to concentrate or dilute urine based on the body's hydration status and is essential in evaluating renal function.

High urine osmolality indicates concentrated urine, which can occur in conditions such as dehydration, where the body conserves water, or in disorders like SIADH (Syndrome of Inappropriate Antidiuretic Hormone Secretion). Conversely, low urine osmolality can suggest conditions where the kidneys are unable to concentrate urine, such as in diabetes insipidus or excessive hydration.

The broader range of 50 to 1400 mOsm/kg captures the physiological variability found in healthy individuals as well as in pathophysiological states. Understanding this range is crucial for laboratory scientists as it helps in diagnosing and managing various renal and systemic conditions.