What is the normal therapeutic range for unfractionated heparin according to the Heparin Assay?

The normal therapeutic range for unfractionated heparin is typically described as 0.3-0.7 in terms of anti-factor Xa activity measured in units per milliliter. This range indicates effective heparin therapy while minimizing the risk of bleeding complications, which is crucial for patient safety.

Monitoring heparin therapy using anti-factor Xa assays is vital for adjusting dosages to maintain this therapeutic range. Values below the range indicate insufficient anticoagulation, increasing the risk of thrombosis, while values above the range raise the risk of bleeding. Therefore, maintaining heparin levels within this specified range ensures both efficacy in preventing thromboembolic events and safety for the patient.